Early Identification of Bronchopulmonary Dysplasia Using Novel Biomarkers by Proteomic Screening
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چکیده
منابع مشابه
Pulmonary Biomarkers of Bronchopulmonary Dysplasia
Bronchopulmonary dysplasia, or BPD, is a chronic pulmonary disorder of premature infants, commonly defined as having an oxygen requirement at 36 weeks postmenstrual age. It is an important source of morbidity and mortality in premature neonates. Its' etiology appears to be multifactorial with the most common associations being prematurity, need for mechanical ventilation, and oxygen exposure. I...
متن کاملBronchopulmonary dysplasia: early diagnosis, prophylaxis, and treatment.
ary dysplasia.2 The incidence of bronchopulmonary dysplasia among ventilated infants varies, depending on gestational age, from 4-2% to as high as 40%,'1 4 but increases up to 70% among infants in whom it is necessary to prolong mechanical ventilation beyond two weeks.5 Such infants have an increased mortality and morbidity even after discharge from neonatal intensive care. Readmission is commo...
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The purpose of this study was to provide a univariate and multivariate analysis of genomic microbial data and salivary mass-spectrometry proteomic profiles for dental caries outcomes. In order to determine potential useful biomarkers for dental caries, a multivariate classification analysis was employed to build predictive models capable of classifying microbial and salivary sample profiles wit...
متن کاملBiomarkers for Bronchopulmonary Dysplasia in the Preterm Infant
Bronchopulmonary dysplasia (BPD) is a chronic inflammatory lung disease of very-low-birth-weight (VLBW) preterm infants, associated with arrested lung development and a need for supplemental oxygen. Over the past few decades, the incidence of BPD has significantly raised as a result of improved survival of VLBW infants requiring mechanical ventilation. While early disease detection is critical ...
متن کاملBronchopulmonary Dysplasia
Bronchopulmonary dysplasia (BPD) continues to be the most common and most important complication in preterm infants with RDS. The incidence varies from 20 to 60 % in preterm infants whose weight are < 1500 gram. The presence of BPD is often associated with significant mortality and short term and long term morbidity, including growth failure and neurodevelopment delay. The exact mechanism and p...
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ژورنال
عنوان ژورنال: American Journal of Respiratory and Critical Care Medicine
سال: 2018
ISSN: 1073-449X,1535-4970
DOI: 10.1164/rccm.201706-1218le